Skin Therapy CALM + DETOX® internal support for symptomatic relief from eczema, dermatitis, rash, poison oak & poison ivy
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Skin Therapy CALM+ DETOX® restores skin health with a powerful combination of 10 concentrated botanical extracts used in traditional herbal medicine to clear inflammation and strengthen the detoxification systems of the body to improve symptoms of irritation, redness, itching and flaking associated with eczema, dermatitis, rash, poison oak and poison ivy.
- Reduces redness and scaly rashes *
- Alleviates itching and dryness *
- 100% Herbal, Steroid-free
- Appropriate for Women, Men & Teens
- Produced in an FDA registered facility in the USA
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Frequently Asked Questions
Skin Therapy Calm + Detox Ingredients
Used extensively in traditional medicine as the foundation herb to address problem skin. Anti-inflammatory, Anti-itch and blood nourishing.
Rehmannia has documented use for over 2000 years and is considered one of the top 50 medicinal Chinese herbs. It is well known for its restorative properties as it is frequently used to enhance regeneration of tissues, provide liver and kidney support, and as the foundation herb to address problem skin. Recent research shows that it exhibits both anti-allergic and anti-inflammatory properties when studied for atopic dermatitis, a chronic inflammatory skin issue. (1)
The primary bioactives in rehmannia are iridoid glycosides. Iridoids are a potent group of phytochemicals that address inflammation. According to the World Health Organization, Rehmannia is well established in pharmacopoeias for use internally to address skin eruptions (2), as a tonic to stimulate the immune system, (3,4,5) and to tonify the detoxification systems of the body (6,7).
Helps control skin toxins and bacteria.
Honeysuckle is widely used in TCM for bacterial infections, skin rashes, and poison oak and ivy as it is one of the most powerful herbs for clearing heat and toxins. Recent research suggests that its antimicrobial and anti-inflammatory activities act to repair wounded and compromised skin.(8)
Honeysuckle is also an excellent source of antioxidants as it’s high in flavonoids and chlorogenic acid – the same powerful free radical inhibitor found in green coffee extract.
Red Root Sage (Salvia)
Helps healing & rejuvenation.
Salvia is one of the most clinically studied herbs in the canon of Chinese medicine. The Divine Farmer’s Materia Medica, one of the oldest works on herbalism, classifies it as one of the top medicinal herbs. It is extensively used in TCM for skin conditions including acne, psoriasis and eczema.
Clinical research shows that salvia exhibits anti-inflammatory, antioxidant, and anti-bacterial activity (9,10,11). Salvia is also known to improve blood circulation and a 2014 study in the journal Molecule found that this medicinal property appears to accelerate repair of damaged skin tissue by providing more nutrients and oxygen to the skin. The study also showed that salvia was able to increase the production of collagen through cell growth-enhancing activity. (12)
Helps cool inflammation.
Gardenia is a tropical plant in the same family as coffee and is one of the most commonly used herbs in Traditional Chinese Medicine (TCM) to cool the body. According to TCM, herbs and food are classified according to whether they have a warming or cooling effect on the body. For example, lemons, apples, watermelon and cucumber are considered cooling while spicy foods and alcohol are considered warming. Herbs that are considered cooling, such as Gardenia, address imbalances by clearing heat and detoxifying the body.
Due to its very strong cold nature, Gardenia is a go-to herb for TCM herbalists treating conditions considered to have excessive heat such as skin infections, bruises, inflammation and pain. Gardenia has been widely studied for its antioxidant properties to protect liver health (13). Recent research also showed that gardenia extract was effective in reducing the inflammatory responses of skin cells. (14).
Helps clear heat and inflammation and antiseptic.
Peony is known as the “Queen of Flowers” and is valued for the Paeoniflorin bio-active, which has an antioxidant effect similar to Vitamin E. One of the mechanisms by which the botanical promotes healthy skin is by preventing lipid peroxidation, the process in which free radicals damage epidermal cells.
Peony was first recorded as an essential extract in the Materia Medica during the Han Dynasty and is frequently used in many classic TCM formulas. It’s been shown in clinical studies to be effective in boosting microcirculation, reducing inflammation and protecting the liver. (15, 16, 17)
Helps clear heat and inflammation and antiseptic.
Skullcap is a powerful, proven cellular regenerator that helps restore your skin. Skullcap is particularly rich in a potent antioxidant flavonoid known as baicalin. Research has shown that baicalin helps repair DNA breaks so that healthy cells can provide structure, strength and resilience to skin. (18-19).
Obtained from the roots of the skullcap plant, baicalin increases skin cell life by restoring telomeres. Telomeres are found at the end of your DNA (like the plastic tips on shoelaces) and protect our genetic data, make it possible for cells to divide, and hold some of the secrets to how we age. Every time a cell divides, the telomeres get shorter. When they get too short, the cell can no longer divide. This shortening process is associated with aging and other diseases.
Baicilin is also shown to protect skin from sun damage. When researchers tried to age skin cells with ultraviolet radiation replicating overexposure to sunlight, the fibroblasts of skin cells treated with baicalin remained youthful and normal. The antioxidant power of baicalin protected the skin cells from free radical damage that causes premature aging of skin.(20)
According to the World Health Organization, skullcap has been used in traditional medicine to treat dermatitis and to stimulate the immune system. It’s known for it’s antiviral, antimicrobial, antioxidant and anti-inflammatory properties. (21)
Helps tonify the liver and detox the skin.
Milkwort, also referred to as Polygala, is one of the 50 fundamental herbs used in TCM and is classified in western texts as a skin conditioner. Milkwort is has been studied for its anti-inflammatory, antioxidant and immune-modulating properties. (22-23). The Traditional Chinese Dermatology textbook instructs that the root is also used to tonify the kidney, improve Qi (energy or life force) and nourish the blood.
In TCM, Qi and blood have a close, interdependent relationship as healthy Qi enables blood to circulate through body to provide energy and whole body nourishment to organs and tissues. The skin needs a healthy supply of fresh blood delivering nutrients and immune cells to remain healthy and to repair wounds. One of the best ways to ensure good blood quality is through a healthy diet of dark, green leafy vegetables and quality organic meat.
Helps tonify the liver and detox the skin.
Cyperus, also known as nutgrass (although unrelated to the nut family), is a very aromatic and tasty herb that was a diet staple for aboriginal populations in Australia and was popular in ancient Egypt and Greece as both a medicine and perfume.
The extract contains flavonoids and beta- Sitosterol that have been shown to be useful for modulating immune cell functions and providing anti-inflammatory and antioxidant effects. The World Journal of Pharmaceutical Research reports that Cyperus is antimicrobial, anti-inflammatory, liver protective, and a potent antioxidant. (24)
In TCM, it’s considered the primary Qi (energy) regulating herb and is frequently used to address skin inflammation, swelling and wounds, along with providing liver support.
Helps relieve itching.
Siler, also known as ledebouriella root, is one of the most effective herbs in traditional medicine to addresses skin itching and hives. Traditional Chinese Medicine (TCM) refers to these conditions as a “wind-type rash” because the itching tends to move around on the body, leading to a vicious itch-scratch cycle.
In TCM, “wind” imbalance is the predominant factor in dermatological disorders such as rash, eczema, boils and hives. Siler is often referred to as the “Wind Protector Root” due to its ability to relieve itching. It also exhibits strong antioxidant and anti-inflammatory properties in clinical studies. (25,26)
Coptis is considered one of the most potent heat clearing herbs in the TCM pharmacy and has many well studied pharmacological effects including antibacterial, antioxidative, anti-inflammatory, and immune stimulating. Coptis is one of the primary sources of the plant alkaloid, berberine, thought to be the source of its antibacterial and anti-inflammatory properties according to the University of Maryland Med Center.
In TCM, it’s frequently used for gastrointestinal issues, liver function and skin disorders. Recent studies support its traditional use, showing positive results for ameliorating oxidative stress of the skin (27) and improving acne by 45% after just four weeks of use. (28)
- J Acupunct Meridian Stud. 2013 Apr;6(2):98-109. doi: 10.1016/j.jams.2012.10.007. Epub 2012 Nov 30. Effects of anti-inflammatory and Rehmanniae radix pharmacopuncture on atopic dermatitis in NC/Nga mice., Kim MC, Lee CH, Yook TH.
- Pharmacopoeia of the People’s Republic of China (English edition). Vol. I. Beijing, Chemical Industry Press, 2000.
- Kim HM et al. Effect of Rehmannia glutinosa on immediate type allergic reaction. International Journal of Immunopharmacology, 1998, 20:231–240.
- Mills, SY. Out of the Earth: The Essential Book of Herbal Medicine Viking Arkana (Penguin), London 1991.
- World Health Organization WHO Monographs on Selected Medicinal Plants, Vol 1. WHO, Geneva, 1999.
- Chang HM, Butt PP. Pharmacology and Applications of Chinese Materia Medica. World Scientific, Singapore, 1987.
- British Herbal Medicine Association. British Herbal Compendium, Vol 1. BHMA, Bournemouth, 1992.
- BMC Complement Altern Med. 2012; 12: 226. Published online 2012 Nov 23. doi: 10.1186/1472-6882-12-226 Wound repair and anti-inflammatory potential of Lonicera japonica in excision wound-induced rats, Wei-Cheng Chen, Shorong-Shii Liou, Thing-Fong Tzeng, Shiow-Ling Lee, and I-Min Liu
- Salvia miltiorrhiza Bunge and its active component cryptotanshinone protects primary cultured rat hepatocytes from acute ethanol-induced cytotoxicity and fatty infiltration. Yin HQ, Choi YJ, Kim YC, Sohn DH, Ryu SY, Lee BH, Food Chem Toxicol. 2009 Jan; 47(1):98-103.
- Comparison of antioxidant activities between salvianolic acid B and Ginkgo biloba extract (EGb 761). Liu CS, Cheng Y, Hu JF, Zhang W, Chen NH, Zhang JT, Acta Pharmacol Sin. 2006 Sep; 27(9):1137-45.
- Genome-wide transcriptional profiling of the response of Staphylococcus aureus to cryptotanshinone. Feng H, Xiang H, Zhang J, Liu G, Guo N, Wang X, Wu X, Deng X, Yu ,L J Biomed Biotechnol. 2009; 2009():617509.
- Molecules 2014, 19(2), 2029-2041; doi:10.3390/molecules19022029, Effects of Danshensu and Salvianolic Acid B from Salvia miltiorrhizaBunge (Lamiaceae) on Cell Proliferation and Collagen and Melanin Production. Yi-Shyan Chen, Shu-Mei Lee, Ying-Ju Lin, Shu-Hua Chiang,* and Chih-Chien Lin
- J Ethnopharmacol. 2015 Aug 22;172:402-9. doi: 10.1016/j.jep.2015.06.043. Epub 2015 Jul 7., Evaluation of the protective effect of Zhi-Zi-da-Huang decoction on acute liver injury with cholestasis induced by α-naphthylisothiocyanate in rats., Chen KL, Bi KS, Han F, Zhu HY, Zhang XS, Mao XJ, Yin R
- Evid Based Complement Alternat Med. 2014;2014:429246. doi: 10.1155/2014/429246. Epub 2014 Mar 11. Gardenia jasminoides Extract Attenuates the UVB-Induced Expressions of Cytokines in Keratinocytes and Indirectly Inhibits Matrix Metalloproteinase-1 Expression in Human Dermal Fibroblasts. Park J, Seok JK, Suh HJ, Boo YC.
- Evid Based Complement Alternat Med. 2009 Mar:6(1): 57-63. Published online 2007, June 15, Screening of Bioactive Compounds from Moutan Cortex and Their Anti-inflammatory Activities in Rat Synoviocytes, Mengjie Wu and Zhiyuan Gu.
- Evid Based Complement Alternat Med. 2007 Sep; 4(3): 327–333. Anti-inflammatory Activity of the Methanol Extract of Moutan Cortex in LPS-Activated Raw264.7 Cells, Seung-Chul Chun, Seon Young Jee, Sang Gon Lee, Sook Jahr Park, Jong Rok Lee, and Sang Chan Kim
- Afr J Tradit Complement Altern Med. 2011; 8(5 Suppl): 220–225. Protective Effects of Moutan Cortex Radicis Against Acute Hepatotoxicity, Juhyun Park, Hyo-Yeon Kim, and Sun-Mee Lee
- Min W, Gao Y, Lin B, Luo D. “Effects of baicalin on ultraviolet A-induced telomere damage in cultured human primary fibroblasts.” Chinese Journal of Dermatology 2011, 44(9) 639-642.
- Chen X, Nishida H, Konishi T. “Baicalin promoted the repair of DNA single strand breakage caused by H2O2 in cultured NIH3T3 fibroblasts.” Biol Pharm Bull. 2003 Feb;26(2):282-4.
- Zhou B, Yin H, Xu Y, Wu D, Zhang Z, Yin Z, Permatasari F, Luo D. “Baicalin protects human skin fibroblasts from ultraviolet A radiation-induced oxidative damage and apoptosis.” Free Radic Res. 2012 Dec;46(12):1458-71.
- World Health Organization, WHO Monographs on Selected Medicinal Plants, Volume 3, p. 283-295. (3rd: 2001: Ottawa, Ont.), ISBN 978 92 4 154702 4
- J Photochem Photobiol B. 2015 May;146:10-7. doi: 10.1016/j.jphotobiol.2015.02.008. Epub 2015 Feb 25., Antioxidant and anti-inflammatory activities of zinc oxide nanoparticles synthesized using Polygala tenuifolia root extract., Nagajyothi PC, Cha SJ, Yang IJ, Sreekanth TV, Kim KJ, Shin HM.
- Altern Med Rev. 2006 Jun;11(2):128-50.Modulation of cytokine expression by traditional medicines: a review of herbal immunomodulators. Spelman K, Burns J, Nichols D, Winters N, Ottersberg S, Tenborg M. Source Clinical Division, Department of Herbal Medicine, Tai Sophia Institute, 7750 Montpelier Road, Laurel, MD 20723, USA.
- Nalini sofia. H, Thomas M.Walter, S. Merish, M. Tamizhamuthu, “An Overview of Nut grass (Cyperus Rotundus) with Special Reference to Ayush”, World Journal of Pharmaceutical Research, Volume 3, Issue 6, 1459-1471, ISSN 2277-7105.
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- BMC Complement Altern Med. 2013; 13: 105. Published online 2013 May 15. doi: 10.1186/1472-6882-13-105 The effect of RHIZOMA COPTIDIS and COPTIS CHINENSIS aqueous extract on radiation-induced skin injury in a rat model Xi-Jing Wang, Shuai Lin, Hua-Feng Kang, Zhi-Jun Dai, Ming-Hua Bai, Xiu-Long Ma, Xiao-Bin Ma, Meng-jie Liu, Xiao-Xu Liu, and Bao-Feng Wang
- Fouladi RF. Aqueous extract of dried fruit of Berberis vulgaris L. in acne vulgaris, a clinical trial. J Diet Suppl. 2012 Dec;9(4):253-61. PMID: 23038982
- Critical Reviews in Food Science and Nutrition, 2011 Apr;51(4):331-62. doi: 10.1080/10408390903584094. Effects of flavonoids and other polyphenols on inflammation. González R, Ballester I, López-Posadas R, Suárez MD, Zarzuelo A, Martínez-Augustin O, Sánchez de Medina F.